DOCS GROW EYE CELLS IN LAB
03 July 2012
Experiment By Chennai Scientists Raises Hope Of Curing Blindness Considered Irreversible
There is new hope for millions of people suffering from "irreversible" blindness due to retinal degeneration or damage. Scientists at Chennai–based Sankara Nethralaya say retinal cells grown from the remains of eyes donated for corneal transplant can be used to correct blindness and retina degeneration.
The scientists said they drew pigment cells from the iris (circular structure in the eye) and ciliary (circumferential tissue) from the donated eyes after the cornea was removed. When these cells were cultured in a petri dish and mixed with growth factors, it produced more cells. Genetic tests showed that these cells resembled and had characters of retinal cells. The study, accepted for publication in the journal Stem Cell Review and Reports, is funded by the department of bio–technology of the Union ministry of science and technology. "This experiment takes us closer to the hope that these cells may be able to cure blindness," said S Krishnakumar, head of Vision Research Foundation at Sankara Nethralaya.
A significant number of the 12 million blind in India suffer from preventable or reversible blindness, but doctors say the prevalence of retinal ailments such as diabetic retinopathy, degeneration and detachment is gradually increasing. Some of these diseases don’t have a cure and leave the affected people with permanent blindness. Across the world, scientists have been pinning their hopes on stem cells for treating retinal diseases. In April 2011, Nature published a report on how retina of rats could be created in a Petri dish from its own stem cells. In January 2012, Lancet reported that scientists used embryonic stem cells to improve the sight of two almost–blind women, a breakthrough that they say raises the hope of a cure for age–related vision loss.
In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues.Stem Cell Treatment Center
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